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While its been popular in other countries around the world, demand stateside has recently grown, prompting the Food and Drug Administration to issue an advisory on injectable skin lightening agents

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This allows it to readily cross the blood-brain barrier (BRR) and offer neuroprotective, neurotrophic and antioxidant properties

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Other afferent blood-borne molecules on the MGB axis include bacterial antigens (242) and inflammatory cytokines such as IL-6, IL-1 and TNF-, which may be produced in a context of gut inflammation